Fokalna infekcija: novo doba ili davna prošlost?

AUTORI:  Pallasch JT, Wahl JM

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Pallasch JT, Wahl JM. Focal infection: new age or ancient history? Endodontic Topics 2003;4:32-45.

A focus of infection is a confined area that: contains pathogenic microorganisms, can occur anywhere in the body and usually causes no clinical manifestations. A focal infection is a localized or generalized infection caused by the dissemination of microorganisms or toxic products from a focus of infection. These concepts have led to the Focal Theory of Infection (or Theory of Focal Infection) that postulates a myriad of diseases caused by microorganisms (bacteria, fungi, viruses) that arise endogenously from a focus of infection. Some have expanded this to include the environment via the concept of antigenic (molecular) mimicry or even to the extent that all diseases are caused by microbes.